Pharma 16 Twin-screw Extruder

The Thermo Scientific™ Pharma 16 Twin-Screw Extruder is a compact and specialized instrument designed specifically for the pharmaceutical industry. Tailored to optimize drug process development in Hot Melt Extrusion (HME) and Twin-Screw Granulation, this extruder is ideal for situations where both lab and production space is limited. Processes developed on the Pharma 16 extruder can be easily scaled up across all pharmaceutical extruders in the Thermo Scientific product family.

Key Features:

1. Compact Design: Specifically designed for the pharmaceutical industry with a focus on compactness, addressing space constraints in both laboratory and production settings.

2. Versatility in Applications:

   • Controlled release formulations
   • Solubility enhancement
   • Co-extrusion and implants
   • Abuse deterrent formulations
   • Wet and melt granulation

3. Scalability: Formulation processes developed on the Pharma 16 extruder can be scaled up across all pharmaceutical extruders in the Thermo Scientific product family, providing consistency and continuity.

4. Adaptability: Designed from the ground up to adapt to the changing needs of the highly regulated pharmaceutical industry, ensuring relevance in evolving processes.

5. GMP Compliance: The compact housing with an optional IP65 protection class is designed to be absolutely crevice-free, meeting optimal Good Manufacturing Practices (GMP) compliance standards.

6. Fully-Ported, Split Twin-Screw Barrel:

   • Eight individual heating and cooling zones
   • Up to 150 bars operational pressure
   • Ensures maximum flexibility in process design

The Thermo Scientific™ Pharma 16 Twin-Screw Extruder is a versatile and adaptable solution for pharmaceutical extrusion, offering a compact design, scalability, and adherence to GMP compliance. Its fully-ported, split twin-screw barrel with precise heating and cooling capabilities provides the flexibility needed for various pharmaceutical applications.